Research workbench
Crystal structure of human ceramide-1-phosphate transfer protein (cptp) in complex with 2:0 ceramide-1-phosphate (2:0-C1P)
Analyse Crystal structure of human ceramide-1-phosphate transfer protein (cptp) in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4K80
- Type
- protein
- Length
- 209 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycolipid transfer protein domain-containing protein 1
- UniProt
- Q5TA50
- Ligands
- 1PW
- Pockets
- 1 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 70% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycolipid transfer protein domain-containing protein 1 | protein | 209 | 70% helix, 2% strand | Q5TA50 |
Ligands and binding sites
- 1PW · (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 202 | 0.71 | 0.87 | 27 | 1PW |
Compared structures
- 4K80 · Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q5TA50 · AlphaFold monomer V2.0 prediction for ceramide-1-phosphate transfer protein (Q5TA50) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5TA50
- Elsewhere: RCSB PDB 4K80 · PDBe 4K80 · UniProt Q5TA50
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