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Crystal structure of mouse cryptochrome 1

Analyse Crystal structure of mouse cryptochrome 1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4K0R
Type: protein
Length: 463 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cryptochrome-1
UniProt: P97784
Pockets: 7 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cryptochrome-1	protein	463	49% helix, 7% strand	P97784

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	285	0.69	0.84	35	empty
2	415	0.63	0.77	35	empty
3	104	0.46	0.79	26	empty
4	86	0.38	0.76	16	empty
5	65	0.36	0.77	12	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4K0R · Crystal structure of mouse Cryptochrome 1 · the same entry in another collection · chain A against A, TM-score 1.00
P97784 · AlphaFold monomer V2.0 prediction for cryptochrome-1 (P97784) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P97784
Elsewhere: RCSB PDB 4K0R · PDBe 4K0R · UniProt P97784

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