Research workbench
Cid of human RPRD1A in complex with a phosphorylated peptide from RPB1-ctd
Analyse Cid of human RPRD1A in complex with a phosphorylated peptide from RPB1-ctd in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4JXT
- Type
- protein
- Length
- 141 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulation of nuclear pre-mRNA domain-containing protein 1A; DNA-directed RNA polymerase…
- EC
- 2.7.7.6, 2.7.7.48
- UniProt
- Q96P16, P24928
- Ligands
- UNX
Structure
x-ray diffraction · 2 distinct chains · 75% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulation of nuclear pre-mRNA domain-containing protein 1A | protein | 130 | 82% helix, 1% strand | Q96P16 |
| B | DNA-directed RNA polymerase II subunit RPB1 (EC 2.7.7.6, 2.7.7.48) | protein | 11 | 0% helix, 9% strand | P24928 |
Ligands and binding sites
- UNX · Unknown atom or ion · ion · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 611 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 4JXT · CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD · the same entry in another collection · chain A against A, TM-score 1.00
- Q96P16 · AlphaFold monomer V2.0 prediction for regulation of nuclear pre-mRNA domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.99
- P24928 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P24928) · a predicted model of the same protein · chain B against A, TM-score 0.38
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96P16
- Every structure of UniProt P24928
- Elsewhere: RCSB PDB 4JXT · PDBe 4JXT · UniProt Q96P16 · UniProt P24928
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.