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Cysteine bound cysteine dioxygenase at pH 8.0 in the presence of cys and dithionite

Analyse Cysteine bound cysteine dioxygenase at pH 8.0 in the presence of cys and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4JTO
Type: protein
Length: 186 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cysteine dioxygenase type 1
EC: 1.13.11.20
UniProt: P21816
Ligands: CYS, FE2
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cysteine dioxygenase type 1 (EC 1.13.11.20)	protein	186	15% helix, 37% strand	P21816

Ligands and binding sites

CYS · Cysteine · ligand · chains A
FE2 · Fe (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	87	0.49	0.82	27	FE2, CYS

Compared structures

4JTO · Cysteine bound Cysteine Dioxygenase at pH 8.0 in the presence of Cys and dithionite · the same entry in another collection · chain A against A, TM-score 1.00
P21816 · AlphaFold monomer V2.0 prediction for cysteine dioxygenase type 1 (P21816) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21816
Elsewhere: RCSB PDB 4JTO · PDBe 4JTO · UniProt P21816

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