UniProt P21816
Cysteine dioxygenase type 1 (P21816)
Cysteine dioxygenase type 1 (UniProt P21816), EC 1.13.11.20: 103 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P21816
- Protein
- Cysteine dioxygenase type 1
- EC
- 1.13.11.20
- Experimental structures
- 103
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 3 · 3 records with a druggable one
Structures
104 records of P21816 in the MolNFT archive: 103 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B5H | 1.5 A Resolution Crystal Structure of Recombinant R. Norvegicus Cysteine Dioxygenase | x-ray diffraction | A | — | — |
| 2B5H | 1.5 a resolution crystal structure of recombinant R. norvegicus cysteine dioxygenase | x-ray diffraction | A | — | — |
| 2GH2 | 1.5 A Resolution R. Norvegicus Cysteine Dioxygenase Structure Crystallized in the Presence of… | x-ray diffraction | A | — | — |
| 2GH2 | 1.5 a resolution R. norvegicus cysteine dioxygenase structure crystallized in the presence of… | x-ray diffraction | A | — | — |
| 3ELN | A Putative Fe2+-bound Persulfenate Intermediate in Cysteine Dioxygenase | x-ray diffraction | A | — | — |
| 3ELN | A putative FE2+-bound persulfenate intermediate in cysteine dioxygenase | x-ray diffraction | A | — | — |
| 4IEO | unliganded Cysteine Dioxygenase at pH 4.0 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IEO | Unliganded cysteine dioxygenase at pH 4.0 in the presence of cys | x-ray diffraction | A | — | — |
| 4IEP | unliganded Cysteine Dioxygenase at pH 4.5 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IEP | Unliganded cysteine dioxygenase at pH 4.5 in the presence of cys | x-ray diffraction | A | — | — |
| 4IEQ | unliganded Cysteine Dioxygenase at pH 5.0 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IEQ | Unliganded cysteine dioxygenase at pH 5.0 in the presence of cys | x-ray diffraction | A | — | — |
| 4IER | Cys-persulfenate bound Cysteine Dioxygenase at pH 5.5 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IER | Cys-persulfenate bound cysteine dioxygenase at pH 5.5 in the presence of cys | x-ray diffraction | A | — | — |
| 4IES | Cys-persulfenate bound Cysteine Dioxygenase at pH 6.2 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IES | Cys-persulfenate bound cysteine dioxygenase at pH 6.2 in the presence of cys | x-ray diffraction | A | — | — |
| 4IET | Cys-persulfenate bound Cysteine Dioxygenase at pH 6.8 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IET | Cys-persulfenate bound cysteine dioxygenase at pH 6.8 in the presence of cys | x-ray diffraction | A | — | — |
| 4IEU | Cys-persulfenate bound Cysteine Dioxygenase at pH 7.0 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IEU | Cys-persulfenate bound cysteine dioxygenase at pH 7.0 in the presence of cys | x-ray diffraction | A | — | — |
| 4IEV | Cys-only bound Cysteine Dioxygenase at pH 8.0 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IEV | Cys-only bound cysteine dioxygenase at pH 8.0 in the presence of cys | x-ray diffraction | A | — | — |
| 4IEW | Cys-only bound Cysteine Dioxygenase at pH 9.0 in the presence of Cys | x-ray diffraction | A | — | — |
| 4IEW | Cys-only bound cysteine dioxygenase at pH 9.0 in the presence of cys | x-ray diffraction | A | — | — |
| 4IEX | unliganded room-temp Cysteine Dioxygenase at pH 6.2 | x-ray diffraction | A | — | — |
| 4IEX | Unliganded room-temp cysteine dioxygenase at pH 6.2 | x-ray diffraction | A | — | — |
| 4IEY | Cys-persulfenate bound Cysteine Dioxygenase at pH 7.0 in the presence of Cys, home-source structure | x-ray diffraction | A | — | — |
| 4IEY | Cys-persulfenate bound cysteine dioxygenase at pH 7.0 in the presence of cys, home-source structure | x-ray diffraction | A | — | — |
| 4IEZ | unliganded Cysteine Dioxygenase at pH 8.0 | x-ray diffraction | A | — | — |
| 4IEZ | Unliganded cysteine dioxygenase at pH 8.0 | x-ray diffraction | A | — | — |
| 4JTN | Cysteine Dioxygenase at pH 8.0 in the presence of dithionite | x-ray diffraction | A | — | — |
| 4JTN | Cysteine dioxygenase at pH 8.0 in the presence of dithionite | x-ray diffraction | A | — | — |
| 4JTO | Cysteine bound Cysteine Dioxygenase at pH 8.0 in the presence of Cys and dithionite | x-ray diffraction | A | — | — |
| 4JTO | Cysteine bound cysteine dioxygenase at pH 8.0 in the presence of cys and dithionite | x-ray diffraction | A | — | — |
| 4KWJ | Resting state of rat cysteine dioxygenase | x-ray diffraction | A | — | — |
| 4KWJ | Resting state of rat cysteine dioxygenase | x-ray diffraction | A | — | — |
| 4KWK | Rat cysteine dioxygenase with cysteine persulfide bound to active site iron | x-ray diffraction | A | — | — |
| 4KWK | Rat cysteine dioxygenase with cysteine persulfide bound to active site iron | x-ray diffraction | A | — | — |
| 4KWL | Rat cysteine dioxygenase with 3-mercaptopropionic acid persulfide bound | x-ray diffraction | A | — | — |
| 4KWL | Rat cysteine dioxygenase with 3-mercaptopropionic acid persulfide bound | x-ray diffraction | A | — | — |
| 4PIX | Unliganded Cysteine Dioxygenase C93A variant at pH 6.2 | x-ray diffraction | A | — | — |
| 4PIX | Unliganded cysteine dioxygenase C93A variant at pH 6.2 | x-ray diffraction | A | — | — |
| 4PIY | Homocysteine bound Cysteine Dioxygenase C93A variant at pH 6.2 | x-ray diffraction | A | — | — |
| 4PIY | Homocysteine bound cysteine dioxygenase C93A variant at pH 6.2 | x-ray diffraction | A | — | — |
| 4PIZ | Homocysteine-bound Cysteine Dioxygenase at pH 6.2 | x-ray diffraction | A | — | — |
| 4PIZ | Homocysteine-bound cysteine dioxygenase at pH 6.2 | x-ray diffraction | A | — | — |
| 4PJY | Azide bound Cysteine Dioxygenase at pH 6.2 | x-ray diffraction | A | — | — |
| 4PJY | Azide bound cysteine dioxygenase at pH 6.2 | x-ray diffraction | A | — | — |
| 4UBG | Resting state of rat cysteine dioxygenase C93G variant | x-ray diffraction | A | — | — |
| 4UBG | Resting state of rat cysteine dioxygenase C93G variant | x-ray diffraction | A | — | — |
| 4UBH | Resting state of rat cysteine dioxygenase Y157F variant | x-ray diffraction | A | — | — |
| 4UBH | Resting state of rat cysteine dioxygenase Y157F variant | x-ray diffraction | A | — | — |
| 4XET | Fe-Cl bound Y157F CDO at pH ~7.0 in the presence of azide | x-ray diffraction | A | — | — |
| 4XET | Fe-cl bound Y157F cdo at pH ~7.0 in the presence of azide | x-ray diffraction | A | — | — |
| 4XEZ | cysteine dioxygenase variant - Y157F at pH 8.0 with dithionite | x-ray diffraction | A | — | — |
| 4XEZ | Cysteine dioxygenase variant - Y157F at pH 8.0 with dithionite | x-ray diffraction | A | — | — |
| 4XF0 | cysteine dioxygenase variant - C93A at pH 8.0 with cysteine | x-ray diffraction | A | — | — |
| 4XF0 | Cysteine dioxygenase variant - C93A at pH 8.0 with cysteine | x-ray diffraction | A | — | — |
| 4XF1 | cysteine dioxygenase variant - Y157F at pH 8.0 with cysteine | x-ray diffraction | A | — | — |
| 4XF1 | Cysteine dioxygenase variant - Y157F at pH 8.0 with cysteine | x-ray diffraction | A | — | — |
44 records more on the page itself.
Ligands
Experiment against prediction
- 6U4V chain A against the predicted model P21816: TM-score 1.00, RMSD 0.33 Å
- 4JTN chain A against the predicted model P21816: TM-score 1.00, RMSD 0.37 Å
- 4JTN chain A against the predicted model P21816: TM-score 1.00, RMSD 0.37 Å
- 6U4S chain A against the predicted model P21816: TM-score 1.00, RMSD 0.36 Å
- 6U4S chain A against the predicted model P21816: TM-score 1.00, RMSD 0.36 Å
- 4XEZ chain A against the predicted model P21816: TM-score 1.00, RMSD 0.38 Å
- 4XEZ chain A against the predicted model P21816: TM-score 1.00, RMSD 0.38 Å
- 4IEZ chain A against the predicted model P21816: TM-score 0.99, RMSD 0.38 Å
- 4IEZ chain A against the predicted model P21816: TM-score 0.99, RMSD 0.38 Å
- 5I0T chain A against the predicted model P21816: TM-score 0.99, RMSD 0.38 Å
Elsewhere
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