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Crystal structure of the N-terminal region of the human ryanodine receptor 2
Analyse Crystal structure of the N-terminal region of the human ryanodine receptor 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4JKQ
- Type
- protein
- Length
- 499 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ryanodine receptor 2
- UniProt
- Q92736
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ryanodine receptor 2 | protein | 499 | 26% helix, 29% strand | Q92736 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 447 | 0.70 | 0.81 | 47 | empty |
| 2 | 272 | 0.56 | 0.77 | 27 | empty |
| 3 | 240 | 0.55 | 0.77 | 24 | empty |
| 4 | 56 | 0.28 | 0.74 | 14 | empty |
Compared structures
- 4JKQ · Crystal structure of the N-terminal region of the human ryanodine receptor 2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92736
- Elsewhere: RCSB PDB 4JKQ · PDBe 4JKQ · UniProt Q92736
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