UniProt Q92736
Ryanodine receptor 2 (Q92736)
Ryanodine receptor 2 (UniProt Q92736): 25 experimental structures on GenesisL1, 5 ligands bound, 423 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q92736
- Protein
- Ryanodine receptor 2
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 423 · 22 records with a druggable one
Structures
25 records of Q92736 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4JKQ | Crystal structure of the N-terminal region of the human ryanodine receptor 2 | x-ray diffraction | A | — | — |
| 4JKQ | Crystal structure of the N-terminal region of the human ryanodine receptor 2 | x-ray diffraction | A | — | — |
| 7KL5 | Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues: Phe4246 to… | x-ray diffraction | B | — | 3 (best 0.58) |
| 7KL5 | Structure of calmodulin bound to the cardiac ryanodine receptor (RYR2) at residues: PHE4246 to… | x-ray diffraction | B | — | — |
| 7U9Q | Structure of PKA phosphorylated human RyR2 in the closed state | electron microscopy | A, D, B, C | ZN, ATP | 20 (best 0.87) |
| 7U9R | Structure of PKA phosphorylated human RyR2 in the open state | electron microscopy | A, D, B, C | ZN, ATP, CA, XAN | 20 (best 0.85) |
| 7U9T | Structure of PKA phosphorylated human RyR2 in the closed state in the presence of Calmodulin | electron microscopy | A, D, B, C | ZN, ATP | 20 (best 0.86) |
| 7U9X | Structure of PKA phosphorylated human RyR2-R2474S in the closed state | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.87) |
| 7U9Z | Structure of PKA phosphorylated human RyR2-R2474S in the open state | electron microscopy | A, B, C, D | ZN, ATP, CA, XAN | 20 (best 0.87) |
| 7UA1 | Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of ARM210 | electron microscopy | A, B, C, D | ZN, ATP, KVR | 20 (best 0.87) |
| 7UA3 | Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of Calmodulin | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.85) |
| 7UA4 | Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin | electron microscopy | A, B, C, D | ZN, ATP, CA, XAN | 20 (best 0.87) |
| 7UA5 | Structure of dephosphorylated human RyR2 in the closed state | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.87) |
| 7UA9 | Structure of dephosphorylated human RyR2 in the open state | electron microscopy | A, B, C, D | ZN, ATP, CA, XAN | 20 (best 0.86) |
| 8UQ2 | Structure of human RyR2-S2808D in the subprimed state | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.87) |
| 8UQ3 | Structure of human RyR2-S2808D in the closed state in the presence of ARM210 | electron microscopy | A, B, C, D | ZN, ATP, KVR | 20 (best 0.84) |
| 8UQ4 | Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.87) |
| 8UXC | Structure of PKA phosphorylated human RyR2-R420Q in the primed state | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.86) |
| 8UXE | Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 | electron microscopy | A, B, C, D | ZN, ATP, KVR | 20 (best 0.81) |
| 8UXF | Structure of PKA phosphorylated human RyR2-R420W in the primed state | electron microscopy | A, B, C, D | ZN, ATP | 20 (best 0.86) |
| 8UXG | Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210 | electron microscopy | A, B, C, D | ZN, ATP, KVR | 20 (best 0.87) |
| 8UXH | Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium | electron microscopy | A, B, C, D | ZN, ATP, CA | 20 (best 0.86) |
| 8UXI | Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium | electron microscopy | A, B, C, D | ZN, ATP, CA | 20 (best 0.87) |
| 8UXL | Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and… | electron microscopy | A, B, C, D | ZN, ATP, CA | 20 (best 0.87) |
| 8UXM | Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and… | electron microscopy | A, B, C, D | ZN, ATP, CA | 20 (best 0.83) |
Ligands
Elsewhere
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