Ligand · KVR
KVR · 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid
KVR, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid (C18 H19 N O3 S, 329.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- KVR
- Formula
- C18 H19 N O3 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 4
Binding sites
KVR in 4 structures; the first of them:
- 7TZC · A drug and ATP binding site in type 1 ryanodine receptor · KVR A5306 · binds HIS879, TRP882, HIS904, CYS906, LEU913, GLU917, ARG918, TYR920 and 1 more
- 7UA1 · Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of… · KVR A5004 · binds TRP893, LYS897, ARG908, GLU928
- 8UXE · Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of… · KVR A5004 · binds TRP893, ASN932, MET935, TRP1007, ASN1029, ARG1031, ARG1041, THR1042 and 3 more
- 8UXG · Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of… · KVR A5004 · binds HIS890, TRP893, LYS897, CYS917, LEU924, GLU928, ASN932, MET935
Residues it binds most
TRP 16, ASN 12, ARG 12, GLU 12, HIS 8, LEU 11, SER 7, CYS 8, LYS 8, MET 8 (residue and the binding sites it lines).
Found with
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