Research workbench
The structure of sterol carrier protein 2 from the yeast yarrowia lipolytica
Analyse The structure of sterol carrier protein 2 from the yeast yarrowia lipolytica in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4JGX
- Type
- protein
- Length
- 247 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fatty acid-binding protein
- UniProt
- P80547
- Ligands
- PLM
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fatty acid-binding protein | protein | 119 | 41% helix, 26% strand | P80547 |
| B | Fatty acid-binding protein | protein | 128 | 43% helix, 24% strand | P80547 |
Ligands and binding sites
- PLM · Palmitic acid · ligand · 2 copies · chains A, B
- CIT · Citric acid · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 196 | 0.74 | 0.89 | 30 | PLM |
| 2 | 319 | 0.66 | 0.81 | 33 | PLM |
Interfaces
1 interface between chains.
- A–B · 737 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 4JGX · The Structure of Sterol Carrier Protein 2 from the Yeast Yarrowia Lipolytica · the same entry in another collection · chain A against A, TM-score 1.00
- P80547 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein (P80547) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P80547
- Elsewhere: RCSB PDB 4JGX · PDBe 4JGX · UniProt P80547
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