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Ring cycle for dilating and constricting the nuclear pore: structure of a NUP54 homo-tetramer.

Analyse Ring cycle for dilating and constricting the nuclear pore: structure of a NUP54… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4J3H
Type: protein
Length: 80 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuclear pore complex protein NUP54
UniProt: P70582
Ligands: CA

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear pore complex protein NUP54	protein	42	69% helix, 0% strand	P70582
B	Nuclear pore complex protein NUP54	protein	38	79% helix, 0% strand	P70582

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 611 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

4J3H · Ring cycle for dilating and constricting the nuclear pore: structure of a Nup54… · the same entry in another collection · chain A against A, TM-score 1.00
P70582 · AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP54 (P70582) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P70582
Elsewhere: RCSB PDB 4J3H · PDBe 4J3H · UniProt P70582

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