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Crystal structure of leishmania mexicana arginase in complex with catalytic product L-ornithine

Analyse Crystal structure of leishmania mexicana arginase in complex with catalytic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4IU5
Type: protein
Length: 310 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Arginase
EC: 3.5.3.1
UniProt: Q6TUJ5
Ligands: ORN, MN
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Arginase (EC 3.5.3.1)	protein	310	43% helix, 16% strand	Q6TUJ5

Ligands and binding sites

ORN · L-ornithine · ligand · chains A
MN · Manganese (II) ion · metal · 2 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	82	0.41	0.79	21	ORN

Compared structures

4IU5 · Crystal structure of Leishmania mexicana arginase in complex with catalytic product… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6TUJ5
Elsewhere: RCSB PDB 4IU5 · PDBe 4IU5 · UniProt Q6TUJ5

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