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Ligand · ORN

ORN · L-ornithine

ORN, L-ornithine (C5 H12 N2 O2, 132.2 g/mol), in the MolNFT structures on GenesisL1: bound in 10 records (10 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
ORN
Formula
C5 H12 N2 O2
Class
ligand
Structures
10
PDB entries
10

Binding sites

ORN in 10 structures; the first of them:

  • 5CKU · Structure of Aspergillus fumigatus ornithine hydroxylase (SidA) mutant N323A bound to… · ORN A603 · binds GLN102, ILE103, LYS107, ASP288, ASN293, PHE296, THR322, LEU467 and 1 more
  • 6TC3 · Cryo-EM structure of an Escherichia coli ribosome-SpeFL complex stalled in response to… · ORN 23S13001 · binds G463, U464, A751, A788, A789, THR4, HIS10, ILE11 and 2 more
  • 6VSU · Arginase from Arabidopsis thaliana in Complex with Ornithine · ORN A404 · binds SER77, HIS187, ASP189, TYR191, PHE194, HIS201, ALA202, HIS284 and 4 more
  • 6X0J · Structure of reduced SidA ornithine hydroxylase with the FAD in" and complexed with NADP… · ORN A602 · binds GLN102, ILE103, LYS107, ASP288, ASN293, PHE296, THR322, ASN323 and 2 more
  • 6X0K · Structure of dithionite-reduced SidA ornithine hydroxylase with the FAD in" and complexed… · ORN A602 · binds GLN102, ILE103, LYS107, ASP288, ASN293, PHE296, THR322, ASN323 and 2 more
  • 7EUK · Crystal structure of N(omega)-hydroxy-L-arginine hydrolase in complex with L-Orn · ORN B403 · binds HIS111, ASP113, ASN115, THR120, THR122, TYR124, GLY126, GLY127 and 3 more
  • 7U6H · HalD with ornithine and alpha-ketoglutarate · ORN A303 · binds VAL79, THR82, ARG87, GLU132, LEU135, HIS146, HIS149, TRP150 and 8 more
  • 7VNT · Structure of aminotransferase-substrate complex · ORN A1002 · binds THR30, ILE63, PHE151, ARG154, GLU236, GLN267, LYS293, THR92 and 4 more
  • 8QEU · Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in… · ORN A401 · binds LEU196, HIS201, ASN231, ASN232, MET233, ASP293, VAL294, SER297 and 5 more
  • 8XJ5 · Crystal structure of AtNATA1 bound to Ornithine and CoA · ORN A301 · binds SER141, PHE142, ARG183, TRP210, GLU49, LEU51, GLU151, ASP152 and 2 more

Residues it binds most

ASN 30, HIS 18, SER 29, THR 27, ASP 27, LEU 21, PHE 23, ILE 19, GLY 13, TRP 6 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol
  • PEG · Di(hydroxyethyl)ether
  • FDA · Dihydroflavine-adenine dinucleotide
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • MG · Magnesium ion
  • MN · Manganese (II) ion
  • NA · Sodium ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol
  • AKG · 2-oxoglutaric acid
  • COA · Coenzyme A
  • FAD · Flavin-adenine dinucleotide

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