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Crystal structure of IML3 from S. cerevisiae

Analyse Crystal structure of IML3 from S. cerevisiae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4IT3
Type: protein
Length: 219 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Central kinetochore subunit IML3
UniProt: P38265
Pockets: 2 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Central kinetochore subunit IML3	protein	219	32% helix, 31% strand	P38265

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.37	0.78	15	empty
2	59	0.30	0.75	11	empty

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

4IT3 · Crystal Structure of Iml3 from S. cerevisiae · the same entry in another collection · chain A against A, TM-score 1.00
P38265 · AlphaFold monomer V2.0 prediction for inner kinetochore subunit IML3 (P38265) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P38265
Elsewhere: RCSB PDB 4IT3 · PDBe 4IT3 · UniProt P38265

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