UniProt P38265
Inner kinetochore subunit IML3 (P38265)
Inner kinetochore subunit IML3 (UniProt P38265): 17 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P38265
- Protein
- Inner kinetochore subunit IML3
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 27 · 7 records with a druggable one
Structures
18 records of P38265 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IT3 | Crystal Structure of Iml3 from S. cerevisiae | x-ray diffraction | A | — | 2 (best 0.37) |
| 4IT3 | Crystal structure of IML3 from S. cerevisiae | x-ray diffraction | A | — | 2 (best 0.37) |
| 4JE3 | An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome… | x-ray diffraction | A | — | 1 (best 0.34) |
| 4JE3 | An IML3-CHL4 heterodimer links the core centromere to factors required for accurate chromosome… | x-ray diffraction | A | — | 1 (best 0.34) |
| 4KR1 | Crystal structure of the kinetechore protein Iml3 from budding yeast | x-ray diffraction | A | — | 1 (best 0.35) |
| 4KR1 | Crystal structure of the kinetechore protein IML3 from budding yeast | x-ray diffraction | A | — | 1 (best 0.35) |
| 6NUW | Yeast Ctf19 complex | electron microscopy | B | — | 1 (best 0.84) |
| 6NUW | Yeast CTF19 complex | electron microscopy | B | — | — |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | L | — | 2 (best 0.72) |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | L | — | — |
| 6QLE | Structure of inner kinetochore CCAN complex | electron microscopy | L | — | 2 (best 0.78) |
| 6QLE | Structure of inner kinetochore ccan complex | electron microscopy | L | — | — |
| 6QLF | Structure of inner kinetochore CCAN complex with mask1 | electron microscopy | L | — | 3 (best 0.76) |
| 6QLF | Structure of inner kinetochore ccan complex with MASK1 | electron microscopy | L | — | — |
| 8OVW | Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA | electron microscopy | L | — | 5 (best 0.85) |
| 8OW0 | Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome | electron microscopy | L | — | 4 (best 0.84) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | LL, L | — | 2 (best 0.83) |
| P38265 | AlphaFold monomer V2.0 prediction for inner kinetochore subunit IML3 (P38265) | predicted | A | — | — |
Experiment against prediction
- 4KR1 chain A against the predicted model P38265: TM-score 0.97, RMSD 1.14 Å
- 4KR1 chain A against the predicted model P38265: TM-score 0.97, RMSD 1.14 Å
- 4IT3 chain A against the predicted model P38265: TM-score 0.96, RMSD 1.13 Å
- 4IT3 chain A against the predicted model P38265: TM-score 0.96, RMSD 1.13 Å
- 6QLF chain L against the predicted model P38265: TM-score 0.96, RMSD 1.37 Å
- 6QLF chain L against the predicted model P38265: TM-score 0.96, RMSD 1.37 Å
- 6QLE chain L against the predicted model P38265: TM-score 0.96, RMSD 1.44 Å
- 6QLE chain L against the predicted model P38265: TM-score 0.96, RMSD 1.44 Å
- 8OVW chain L against the predicted model P38265: TM-score 0.95, RMSD 1.53 Å
- 6QLD chain L against the predicted model P38265: TM-score 0.95, RMSD 1.52 Å
Elsewhere
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