Research workbench
Polycrystalline T6 bovine insulin: anisotropic lattice evolution and novel structure refinement strategy
Analyse Polycrystalline T6 bovine insulin: anisotropic lattice evolution and novel… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4IDW
- Type
- protein
- Length
- 102 residues
- Chains
- 4
- Method
- powder diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Insulin a chain; Insulin B chain
- UniProt
- P01317
- Ligands
- ZN
Structure
powder diffraction · 2 distinct chains · 43% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Insulin a chain | protein | 21 | 57% helix, 10% strand | P01317 |
| B, D | Insulin B chain | protein | 30 | 33% helix, 13% strand | P01317 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
5 interfaces between chains.
- C–D · 908 Ų buried · 15 hydrogen bonds · protein-protein
- A–B · 867 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 666 Ų buried · 10 hydrogen bonds · protein-protein
- B–C · 53 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 47 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 4IDW · Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure… · the same entry in another collection · chain A against A, TM-score 1.00
- P01317 · AlphaFold monomer V2.0 prediction for insulin (P01317) · a predicted model of the same protein · chain B against A, TM-score 0.38
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01317
- Elsewhere: RCSB PDB 4IDW · PDBe 4IDW · UniProt P01317
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