UniProt P01317
Insulin A chain (P01317)
Insulin A chain (UniProt P01317): 69 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01317
- Protein
- Insulin A chain
- Experimental structures
- 69
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 0 records with a druggable one
Structures
70 records of P01317 in the MolNFT archive: 69 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1APH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1APH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1BPH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1BPH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1CPH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1CPH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1DPH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1DPH | Conformational changes in cubic insulin crystals in the pH range 7-11 | x-ray diffraction | A, B | — | — |
| 1HO0 | New B-chain mutant of bovine insulin | solution nmr | A | — | — |
| 1HO0 | New B-chain mutant of bovine insulin | solution nmr | A | — | — |
| 1PID | Bovine despentapeptide insulin | x-ray diffraction | A, B, C, D | — | — |
| 1PID | Bovine despentapeptide insulin | x-ray diffraction | A, B, C, D | — | — |
| 2A3G | The structure of T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 2A3G | The structure of T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 2BN1 | Insulin after a high dose x-ray burn | x-ray diffraction | A, B | — | — |
| 2BN1 | Insulin after a high dose X-ray burn | x-ray diffraction | A, B | — | — |
| 2BN3 | Insulin before a high dose x-ray burn | x-ray diffraction | A, B | — | — |
| 2BN3 | Insulin before a high dose X-ray burn | x-ray diffraction | A, B | — | — |
| 2INS | The structure of des-phe B1 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 2INS | The structure of des-phe B1 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 2ZP6 | Crystal structure of Bovine Insulin (Hexameric form) | x-ray diffraction | A, B, C, D | — | — |
| 2ZP6 | Crystal structure of bovine insulin (hexameric form) | x-ray diffraction | A, B, C, D | — | — |
| 4BS3 | Bovin insulin structure determined by in situ crystal analysis and sulfur-SAD phasing at room… | x-ray diffraction | A, B | — | — |
| 4BS3 | Bovin insulin structure determined by in situ crystal analysis and sulfur-sad phasing at room… | x-ray diffraction | A, B | — | — |
| 4E7T | The structure of T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4E7T | The structure of T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4E7U | The structure of T3R3 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4E7U | The structure of T3R3 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4E7V | The structure of R6 bovine insulin | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, 1, 2, 3, 4, 5, 6 | — | — |
| 4E7V | The structure of R6 bovine insulin | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, 1, 2, 3, 4, 5, 6 | — | — |
| 4I5Y | Insulin protein crystallization via langmuir-blodgett | x-ray diffraction | A, B | — | — |
| 4I5Y | Insulin protein crystallization via langmuir-blodgett | x-ray diffraction | A, B | — | — |
| 4I5Z | Insulin protein crystallization via langmuir-blodgett | x-ray diffraction | A, B | — | — |
| 4I5Z | Insulin protein crystallization via langmuir-blodgett | x-ray diffraction | A, B | — | — |
| 4IDW | Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement… | powder diffraction | A, B, C, D | — | — |
| 4IDW | Polycrystalline T6 bovine insulin: anisotropic lattice evolution and novel structure refinement… | powder diffraction | A, B, C, D | — | — |
| 4IHN | High Resolution Insulin by Langmuir-Blodgett Modified Hanging Drop Vapour Diffusion | x-ray diffraction | A, B | — | — |
| 4IHN | High resolution insulin by langmuir-blodgett modified hanging drop vapour diffusion | x-ray diffraction | A, B | — | — |
| 4M4F | Radiation damage study of Cu T6-insulin - 0.01 MGy | x-ray diffraction | A, B, C, D | — | — |
| 4M4F | Radiation damage study of cu T6-insulin - 0.01 mgy | x-ray diffraction | A, B, C, D | — | — |
| 4M4H | Radiation damage study of Cu T6-insulin - 0.06 MGy | x-ray diffraction | A, B, C, D | — | — |
| 4M4H | Radiation damage study of cu T6-insulin - 0.06 mgy | x-ray diffraction | A, B, C, D | — | — |
| 4M4I | Radiation damage study of Cu T6-insulin - 0.12 MGy | x-ray diffraction | A, B, C, D | — | — |
| 4M4I | Radiation damage study of cu T6-insulin - 0.12 mgy | x-ray diffraction | A, B, C, D | — | — |
| 4M4J | Radiation damage study of Cu T6-insulin - 0.30 MGy | x-ray diffraction | A, B, C, D | — | — |
| 4M4J | Radiation damage study of cu T6-insulin - 0.30 mgy | x-ray diffraction | A, B, C, D | — | — |
| 4M4L | The structure of Cu T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4M4L | The structure of cu T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4M4M | The structure of Ni T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 4M4M | The structure of ni T6 bovine insulin | x-ray diffraction | A, B, C, D | — | — |
| 5AZZ | Crystal structure of seleno-insulin | x-ray diffraction | A, B | — | — |
| 5AZZ | Crystal structure of seleno-insulin | x-ray diffraction | A, B | — | — |
| 5KQV | Insulin receptor ectodomain construct comprising domains L1,CR,L2, fniii-1 and alphact peptide in… | x-ray diffraction | A, B, I, J | — | — |
| 5MIZ | MD ensemble of bovine insulin | solution nmr | A, B | — | — |
| 5MIZ | Md ensemble of bovine insulin | solution nmr | A, B | — | — |
| 6KH8 | Solution structure of zn free bovine pancreatic insulin in 20% acetic acid-D4 (pH 1.9) | solution nmr | A, B | — | — |
| 6KH9 | Solution structure of bovine insulin amyloid intermediate-1 | solution nmr | A, B | — | 1 (best 0.30) |
| 6KH9 | Solution structure of bovine insulin amyloid intermediate-1 | solution nmr | A, B | — | — |
| 6KHA | Solution structure of bovine insulin amyloid intermediate-2 | solution nmr | A, B | — | — |
| 6OR0 | Crystal structure of insulin from non-merohedrally twinned crystals | x-ray diffraction | A, B | — | — |
10 records more on the page itself.
Ligands
Experiment against prediction
- 4E7V chain B against the predicted model P01317: TM-score 0.51, RMSD 1.78 Å
- 4E7V chain B against the predicted model P01317: TM-score 0.51, RMSD 1.78 Å
- 4E7U chain D against the predicted model P01317: TM-score 0.50, RMSD 1.77 Å
- 4E7U chain D against the predicted model P01317: TM-score 0.50, RMSD 1.77 Å
- 4M4J chain B against the predicted model P01317: TM-score 0.43, RMSD 1.46 Å
- 4M4F chain B against the predicted model P01317: TM-score 0.43, RMSD 1.47 Å
- 4M4F chain B against the predicted model P01317: TM-score 0.43, RMSD 1.47 Å
- 4M4H chain B against the predicted model P01317: TM-score 0.43, RMSD 1.44 Å
- 4M4I chain D against the predicted model P01317: TM-score 0.43, RMSD 1.52 Å
- 4M4H chain D against the predicted model P01317: TM-score 0.43, RMSD 1.52 Å
Elsewhere
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