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A vertebrate cryptochrome

Analyse A vertebrate cryptochrome in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4I6E
Type: protein
Length: 471 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cryptochrome-2
UniProt: Q9R194
Pockets: 3 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cryptochrome-2	protein	471	47% helix, 6% strand	Q9R194

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	607	0.73	0.80	39	empty
2	388	0.71	0.83	41	empty
3	138	0.56	0.82	30	empty

Compared structures

4I6E · A vertebrate cryptochrome · the same entry in another collection · chain A against A, TM-score 1.00
Q9R194 · AlphaFold monomer V2.0 prediction for cryptochrome-2 (Q9R194) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9R194
Elsewhere: RCSB PDB 4I6E · PDBe 4I6E · UniProt Q9R194

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