Research workbench
Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant D61N
Analyse Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4I3N
- Type
- protein
- Length
- 482 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ryanodine receptor 1
- UniProt
- P11716
- Pockets
- 3 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ryanodine receptor 1 | protein | 482 | 28% helix, 30% strand | P11716 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 664 | 0.74 | 0.80 | 78 | empty |
| 2 | 134 | 0.41 | 0.75 | 22 | empty |
| 3 | 55 | 0.33 | 0.78 | 18 | empty |
Compared structures
- 4I3N · Crystal structure of rabbit ryanodine receptor 1 (residues 1-536) disease mutant D61N · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11716
- Elsewhere: RCSB PDB 4I3N · PDBe 4I3N · UniProt P11716
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