Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with by-product

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 19% strand (DSSP).

Ligands and binding sites

• UD7 · [(2R,3R,4R,6R)-3-acetamido-6-methyl-4-oxidanyl-5-oxidanylidene-oxan-2-yl] [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate · ligand · 2 copies · chains A
• NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
• NA · Sodium ion · metal · chains A
• FMT · Formic acid · additive · 14 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Compared structures

• 4G5H · Crystal structure of capsular polysaccharide synthesizing enzyme CapE from Staphylococcus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q7A2Y4
• Elsewhere: RCSB PDB 4G5H · PDBe 4G5H · UniProt Q7A2Y4