Research workbench
Crystal structure of yeast DNA polymerase alpha
Analyse Crystal structure of yeast DNA polymerase alpha in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4FVM
- Type
- protein
- Length
- 829 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA polymerase alpha catalytic subunit a
- EC
- 2.7.7.7
- UniProt
- P13382
- Pockets
- 12 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase alpha catalytic subunit a (EC 2.7.7.7) | protein | 829 | 39% helix, 22% strand | P13382 |
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 918 | 0.74 | 0.77 | 98 | empty |
| 2 | 161 | 0.67 | 0.87 | 27 | empty |
| 3 | 358 | 0.64 | 0.79 | 41 | empty |
| 4 | 366 | 0.62 | 0.78 | 53 | empty |
| 5 | 322 | 0.61 | 0.78 | 32 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13382
- Elsewhere: RCSB PDB 4FVM · PDBe 4FVM · UniProt P13382
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