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Structure of chicken annexin V at 2.25-ångströms resolution

Analyse Structure of chicken annexin V at 2.25-ångströms resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ALA
Type: protein
Length: 316 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Annexin V
UniProt: P17153
Ligands: CA
Pockets: 4 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Annexin V	protein	316	71% helix, 0% strand	P17153

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	235	0.62	0.81	18	empty
2	194	0.57	0.80	31	empty
3	107	0.51	0.82	22	empty
4	121	0.44	0.77	15	empty

Compared structures

1ALA · Structure of chicken annexin V at 2.25-ångströms resolution · the same entry in another collection · chain A against A, TM-score 1.00
P17153 · AlphaFold monomer V2.0 prediction for annexin A5 (P17153) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17153
Elsewhere: RCSB PDB 1ALA · PDBe 1ALA · UniProt P17153

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