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Nucleoporin NUP37 from schizosaccharomyces pombe

Analyse Nucleoporin NUP37 from schizosaccharomyces pombe in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4FHL
Type: protein
Length: 345 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoporin NUP37
UniProt: O36030
Ligands: SO4
Pockets: 1 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoporin NUP37	protein	345	3% helix, 57% strand	O36030

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A
EDO · 1,2-ethanediol · additive · 7 copies · chains A
BU1 · 1,4-butanediol · additive · chains A
DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	907	0.78	0.80	69	EDO

Compared structures

4FHL · Nucleoporin Nup37 from Schizosaccharomyces pombe · the same entry in another collection · chain A against A, TM-score 1.00
O36030 · AlphaFold monomer V2.0 prediction for uncharacterized wd repeat- containing protein… · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O36030
Elsewhere: RCSB PDB 4FHL · PDBe 4FHL · UniProt O36030

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