Research workbench
Crystal structure of chondroitin ABC lyase I from proteus vulgaris at 1.9 ångströms resolution
Analyse Crystal structure of chondroitin ABC lyase I from proteus vulgaris at 1.9… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HN0
- Type
- protein
- Length
- 971 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chondroitin ABC lyase I
- EC
- 4.2.2.4
- UniProt
- P59807
- Ligands
- NA
- Pockets
- 7 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chondroitin ABC lyase I (EC 4.2.2.4) | protein | 971 | 27% helix, 30% strand | P59807 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 51 | 0.62 | 0.94 | 23 | empty |
| 2 | 139 | 0.43 | 0.76 | 26 | empty |
| 3 | 85 | 0.35 | 0.75 | 21 | empty |
| 4 | 88 | 0.33 | 0.74 | 22 | empty |
| 5 | 70 | 0.32 | 0.75 | 16 | empty |
Compared structures
- 1HN0 · Crystal structure of chondroitin ABC lyase I from proteus vulgaris at 1.9 ångströms… · the same entry in another collection · chain A against A, TM-score 1.00
- P59807 · AlphaFold monomer V2.0 prediction for chondroitin sulfate ABC endolyase (P59807) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59807
- Elsewhere: RCSB PDB 1HN0 · PDBe 1HN0 · UniProt P59807
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