Research workbench
ATPase domain of human heat shock 70KDA protein 1
Analyse ATPase domain of human heat shock 70KDA protein 1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1HJO
- Type
- protein
- Length
- 380 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (heat-shock 70KD protein)
- EC
- 3.6.1.3
- UniProt
- P08107
- Ligands
- ADP, CA, CL
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (heat-shock 70KD protein) (EC 3.6.1.3) | protein | 380 | 40% helix, 28% strand | P08107 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- CA · Calcium ion · metal · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 691 | 0.77 | 0.82 | 68 | CA, ADP |
| 2 | 50 | 0.45 | 0.84 | 13 | empty |
Compared structures
- 1HJO · ATPase domain of human heat shock 70kDa protein 1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08107
- Elsewhere: RCSB PDB 1HJO · PDBe 1HJO · UniProt P08107
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