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Crystal structure of two tandem RNA recognition motifs of human antigen R

Analyse Crystal structure of two tandem RNA recognition motifs of human antigen R in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4EGL
Type: protein
Length: 165 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Elav-like protein 1
UniProt: Q15717
Ligands: SO4
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Elav-like protein 1	protein	165	27% helix, 35% strand	Q15717

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A
GOL · Glycerol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	91	0.35	0.75	15	SO4

Modifications

Observed in the structure: 1 modified (methylation).

Compared structures

4EGL · Crystal structure of two tandem RNA recognition motifs of Human antigen R · the same entry in another collection · chain A against A, TM-score 1.00
Q15717 · AlphaFold monomer V2.0 prediction for elav-like protein 1 (Q15717) · a predicted model of the same protein · chain A against A, TM-score 0.56

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15717
Elsewhere: RCSB PDB 4EGL · PDBe 4EGL · UniProt Q15717

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