Research workbench
Crystal structure of the ig-pH domain of actin-binding protein SCAB1
Analyse Crystal structure of the ig-pH domain of actin-binding protein SCAB1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4DIX
- Type
- protein
- Length
- 424 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plectin-related protein
- UniProt
- O48791
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 17% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Plectin-related protein | protein | 212 | 17% helix, 45% strand | O48791 |
Ligands and binding sites
- MLI · Malonate ion · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 109 | 0.53 | 0.82 | 27 | empty |
| 2 | 95 | 0.50 | 0.83 | 20 | empty |
| 3 | 107 | 0.37 | 0.74 | 26 | empty |
| 4 | 53 | 0.26 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 615 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 4DIX · Crystal structure of the Ig-PH domain of actin-binding protein SCAB1 · the same entry in another collection · chain A against A, TM-score 1.00
- O48791 · AlphaFold monomer V2.0 prediction for stomatal closure-related actin- binding protein 1… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O48791
- Elsewhere: RCSB PDB 4DIX · PDBe 4DIX · UniProt O48791
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.