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Crystal structure of beclin 1 evolutionarily conserved DOMAIN(ECD)

Analyse Crystal structure of beclin 1 evolutionarily conserved DOMAIN(ECD) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4DDP
Type: protein
Length: 195 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beclin-1
UniProt: Q14457
Pockets: 2 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beclin-1	protein	195	45% helix, 15% strand	Q14457

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.51	0.81	21	empty
2	66	0.31	0.75	14	empty

Compared structures

4DDP · crystal structure of Beclin 1 evolutionarily conserved domain(ECD) · the same entry in another collection · chain A against A, TM-score 1.00
Q14457 · AlphaFold monomer V2.0 prediction for beclin-1 (Q14457) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14457
Elsewhere: RCSB PDB 4DDP · PDBe 4DDP · UniProt Q14457

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