UniProt Q14457
Beclin-1 (Q14457)
Beclin-1 (UniProt Q14457): 28 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14457
- Protein
- Beclin-1
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 3 records with a druggable one
Structures
29 records of Q14457 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2P1L | Structure of the Bcl-XL:Beclin 1 complex | x-ray diffraction | B, D, F, H | — | — |
| 2P1L | Structure of the BCL-XL:BECLIN 1 complex | x-ray diffraction | B, D, F, H | — | — |
| 2PON | Solution structure of the Bcl-xL/Beclin-1 complex | solution nmr | A | — | — |
| 2PON | Solution structure of the BCL-XL/BECLIN-1 complex | solution nmr | A | — | — |
| 3DVU | Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and the Beclin 1… | x-ray diffraction | C, D | — | — |
| 3DVU | Crystal structure of the complex of murine gamma-herpesvirus 68 BCL-2 homolog M11 and the beclin 1… | x-ray diffraction | C, D | — | — |
| 4DDP | crystal structure of Beclin 1 evolutionarily conserved domain(ECD) | x-ray diffraction | A | — | — |
| 4DDP | Crystal structure of beclin 1 evolutionarily conserved DOMAIN(ECD) | x-ray diffraction | A | — | — |
| 4MI8 | Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1… | x-ray diffraction | C, D | — | — |
| 4MI8 | Crystal structure of the complex of murine gamma-herpesvirus 68 BCL-2 homolog M11 and a beclin 1… | x-ray diffraction | C, D | — | — |
| 5EFM | Beclin 1 Flexible-helical Domian (FHD) (141-171) | x-ray diffraction | A | SO4 | — |
| 5EFM | Beclin 1 flexible-helical domian (fhd) (141-171) | x-ray diffraction | A | — | — |
| 5HHE | Human Beclin 1 coiled-coil domain | x-ray diffraction | D, A | — | — |
| 5HHE | Human beclin 1 coiled-coil domain | x-ray diffraction | D, A | — | — |
| 5VAU | BCL-2 complex with beclin 1 BH3 domain | x-ray diffraction | E, G, F, H | — | — |
| 5VAX | BCL-2 complex with beclin 1 BH3 domain | x-ray diffraction | E, F, G, H | — | — |
| 5VAY | BCL-2 complex with beclin 1 T108D BH3 domain | x-ray diffraction | E, G, F, H | — | — |
| 6DCN | Bcl-xL complex with Beclin 1 BH3 domain T108pThr | x-ray diffraction | D, C | — | — |
| 6DCN | BCL-xl complex with beclin 1 BH3 domain T108PTHR | x-ray diffraction | D, C | — | — |
| 6DCO | BCL-xl complex with beclin 1 BH3 domain T108D | x-ray diffraction | C, D | — | — |
| 6HOI | Structure of Beclin1 LIR motif bound to GABARAPL1 | x-ray diffraction | F, G | — | — |
| 6HOI | Structure of BECLIN1 lir motif bound to GABARAPL1 | x-ray diffraction | F, G | — | — |
| 6HOJ | Structure of BECLIN1 lir motif bound to gabarap | x-ray diffraction | A, B, C | SO4 | — |
| 6HOK | Structure of Beclin1 LIR (S96E) motif bound to GABARAP | x-ray diffraction | A | — | — |
| 6HOK | Structure of BECLIN1 lir (S96E) motif bound to gabarap | x-ray diffraction | A | — | — |
| 7BL1 | human complex II-BATS bound to membrane-attached Rab5a-GTP | electron microscopy | EEE | — | 4 (best 0.77) |
| 8SOR | Structure of human PI3KC3-C1 complex | electron microscopy | D | — | 6 (best 0.82) |
| 9C82 | Structure of human ULK1C:PI3KC3-C1 supercomplex | electron microscopy | D | — | 6 (best 0.80) |
| Q14457 | AlphaFold monomer V2.0 prediction for beclin-1 (Q14457) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 6HOK chain A against the predicted model O95166: TM-score 0.87, RMSD 0.49 Å
- 6HOK chain A against the predicted model O95166: TM-score 0.87, RMSD 0.49 Å
- 6HOJ chain A against the predicted model O95166: TM-score 0.89, RMSD 0.51 Å
- 6HOJ chain C against the predicted model O95166: TM-score 0.89, RMSD 0.59 Å
- 6HOJ chain B against the predicted model O95166: TM-score 0.88, RMSD 0.86 Å
- 4DDP chain A against the predicted model Q14457: TM-score 0.88, RMSD 1.84 Å
- 4DDP chain A against the predicted model Q14457: TM-score 0.88, RMSD 1.84 Å
- 5HHE chain D against the predicted model Q14457: TM-score 0.86, RMSD 1.47 Å
- 5HHE chain D against the predicted model Q14457: TM-score 0.86, RMSD 1.47 Å
- 5HHE chain A against the predicted model Q14457: TM-score 0.85, RMSD 1.59 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.