Direct visualisation of strain-induced protein prost-translational modification

Structure

x-ray diffraction · 2 distinct chains · 20% helix, 43% strand (DSSP).

Ligands and binding sites

• ACO · Acetyl coenzyme *A · ligand · chains A, B
• MG · Magnesium ion · metal · chains B
• SCN · Thiocyanate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• A–B · 674 Ų buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide, 1 modified (disulfide, oxidation).

Compared structures

• 4CRZ · Direct visualisation of strain-induced protein prost-translational modification · the same entry in another collection · chain A against A, TM-score 1.00
• P0A790 · AlphaFold monomer V2.0 prediction for aspartate 1-decarboxylase (P0A790) · a predicted model of the same protein · chain A against A, TM-score 0.99
• P37613 · AlphaFold monomer V2.0 prediction for pand regulatory factor (P37613) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P0A790
• Every structure of UniProt P37613
• Elsewhere: RCSB PDB 4CRZ · PDBe 4CRZ · UniProt P0A790 · UniProt P37613