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Crystal structure of the Fab portion of olokizumab in complex with il- 6

Analyse Crystal structure of the Fab portion of olokizumab in complex with il- 6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4CNI
Type
protein
Length
1,209 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P05231

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein220——
B, L—protein214——
C, D—protein171—P05231
H—protein219——

Compared structures

  • 4CNI · Crystal structure of the Fab portion of Olokizumab in complex with IL- 6 · the same entry in another collection · chain C against C, TM-score 1.00
  • P05231 · AlphaFold monomer V2.0 prediction for interleukin-6 (P05231) · a predicted model of the same protein · chain C against A, TM-score 0.97

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