UniProt P05231
Interleukin-6 (P05231)
Interleukin-6 (UniProt P05231): 25 experimental structures on GenesisL1, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P05231
- Protein
- Interleukin-6
- Experimental structures
- 25
- Predicted models
- 0
- Pockets
- 8 · 2 records with a druggable one
Structures
25 records of P05231 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ALU | Human interleukin-6 | x-ray diffraction | A | — | — |
| 1ALU | Human interleukin-6 | x-ray diffraction | A | — | — |
| 1IL6 | Human interleukin-6, NMR, minimized average structure | solution nmr | A | — | — |
| 1IL6 | Human interleukin-6, NMR, minimized average structure | solution nmr | A | — | — |
| 1P9M | Crystal structure of the hexameric human IL-6/IL-6 alpha receptor/gp130 complex | x-ray diffraction | B | — | — |
| 1P9M | Crystal structure of the hexameric human il-6/IL-6 alpha RECEPTOR/GP130 complex | x-ray diffraction | B | — | — |
| 2IL6 | Human interleukin-6, NMR, 32 structures | solution nmr | A | — | — |
| 2IL6 | Human interleukin-6, NMR, 32 structures | solution nmr | A | — | — |
| 4CNI | Crystal structure of the Fab portion of Olokizumab in complex with IL- 6 | x-ray diffraction | C, D | — | — |
| 4CNI | Crystal structure of the Fab portion of olokizumab in complex with il- 6 | x-ray diffraction | C, D | — | — |
| 4J4L | Modular evolution and design of the protein binding interface | x-ray diffraction | C, D | — | — |
| 4J4L | Modular evolution and design of the protein binding interface | x-ray diffraction | C, D | — | — |
| 4NI7 | Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER… | x-ray diffraction | A | — | — |
| 4NI7 | Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (somamer… | x-ray diffraction | A | — | — |
| 4NI9 | Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER… | x-ray diffraction | A, C | — | — |
| 4NI9 | Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (somamer… | x-ray diffraction | A, C | — | — |
| 4O9H | Structure of Interleukin-6 in complex with a Camelid Fab fragment | x-ray diffraction | A | — | — |
| 4O9H | Structure of interleukin-6 in complex with a camelid Fab fragment | x-ray diffraction | A | — | — |
| 4ZS7 | Structural mimicry of receptor interaction by antagonistic IL-6 antibodies | x-ray diffraction | A | — | — |
| 4ZS7 | Structural mimicry of receptor interaction by antagonistic il-6 antibodies | x-ray diffraction | A | — | — |
| 5FUC | Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80… | x-ray diffraction | A, B | — | — |
| 5FUC | Biophysical and cellular characterisation of a junctional epitope antibody that locks il-6 and GP80… | x-ray diffraction | A, B | — | — |
| 8QY5 | Structure of interleukin 6. | electron microscopy | B, E | — | 7 (best 0.76) |
| 8YWR | Crystal structure of the Fab fragment of the anti-IL-6 antibody 68F2 in complex with a… | x-ray diffraction | A | — | 1 (best 0.73) |
| P05231 | AlphaFold monomer V2.0 prediction for interleukin-6 (P05231) | — | — | — |
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.