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Structure of human COFILIN1

Analyse Structure of human COFILIN1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4BEX
Type: protein
Length: 166 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cofilin-1
UniProt: P23528
Pockets: 2 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
1	Cofilin-1	protein	166	33% helix, 30% strand	P23528

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.30	0.74	14	empty
2	53	0.27	0.74	15	empty

Compared structures

4BEX · Structure of human Cofilin1 · the same entry in another collection · chain 1 against 1, TM-score 1.00
P23528 · AlphaFold monomer V2.0 prediction for cofilin-1 (P23528) · a predicted model of the same protein · chain 1 against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23528
Elsewhere: RCSB PDB 4BEX · PDBe 4BEX · UniProt P23528

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