Research workbench
Discovery and optimization of new benzimidazole- and benzoxazole- pyrimidone selective PI3KBETA inhibitors for the treatment of phosphatase and tensin homologue (pten)-deficient cancers
Analyse Discovery and optimization of new benzimidazole- and benzoxazole- pyrimidone… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4AJW
- Type
- protein
- Length
- 1,557 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O35904
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 765 | — | O35904 |
| B | — | protein | 792 | — | O35904 |
Compared structures
- 4AJW · Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective… · the same entry in another collection · chain A against A, TM-score 1.00
- O35904 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35904
- Elsewhere: RCSB PDB 4AJW · PDBe 4AJW · UniProt O35904
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