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X-ray crystal structure of porcine insulin flash-cooled at high pressure

Analyse X-ray crystal structure of porcine insulin flash-cooled at high pressure in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4A7E
Type
protein
Length
50 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Insulin a chain; Insulin B chain
UniProt
P01315

Structure

x-ray diffraction · 2 distinct chains · 54% helix, 4% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AInsulin a chainprotein2162% helix, 5% strandP01315
BInsulin B chainprotein2948% helix, 3% strandP01315

Interfaces

1 interface between chains.

  • A–B · 824 Ų buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 4A7E · X-ray crystal structure of porcine insulin flash-cooled at high pressure · the same entry in another collection · chain A against A, TM-score 1.00

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