Research workbench
Radixin complex
Analyse Radixin complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3X23
- Type
- protein
- Length
- 310 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Radixin; Peptide from matrix metalloproteinase-14
- UniProt
- P26043, P50281
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Radixin | protein | 299 | 36% helix, 24% strand | P26043 |
| B | Peptide from matrix metalloproteinase-14 | protein | 11 | 0% helix, 64% strand | P50281 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 347 | 0.60 | 0.77 | 27 | empty |
| 2 | 274 | 0.54 | 0.76 | 31 | empty |
| 3 | 86 | 0.37 | 0.77 | 19 | empty |
| 4 | 84 | 0.35 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 730 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 3X23 · Radixin complex · the same entry in another collection · chain A against A, TM-score 1.00
- P26043 · AlphaFold monomer V2.0 prediction for radixin (P26043) · a predicted model of the same protein · chain A against A, TM-score 0.97
- P50281 · AlphaFold monomer V2.0 prediction for matrix metalloproteinase-14 (P50281) · a predicted model of the same protein · chain B against A, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26043
- Every structure of UniProt P50281
- Elsewhere: RCSB PDB 3X23 · PDBe 3X23 · UniProt P26043 · UniProt P50281
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