UniProt P50281
Matrix metalloproteinase-14 (P50281)
Matrix metalloproteinase-14 (UniProt P50281), EC 3.4.24.80: 23 experimental structures on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P50281
- Protein
- Matrix metalloproteinase-14
- EC
- 3.4.24.80
- Experimental structures
- 23
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 1 · 1 record with a druggable one
Structures
23 records of P50281 in the MolNFT archive: 23 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BQQ | Crystal structure of the MT1-mmp--timp-2 complex | x-ray diffraction | M | — | — |
| 1BQQ | Crystal structure of the MT1-mmp--timp-2 complex | x-ray diffraction | M | — | — |
| 1BUV | Crystal structure of the MT1-mmp-timp-2 complex | x-ray diffraction | M | — | — |
| 1BUV | Crystal structure of the MT1-mmp-timp-2 complex | x-ray diffraction | M | — | — |
| 2MQS | Transient Collagen Triple Helix Binding to a Key Metalloproteinase in Invasion and Development… | solution nmr | A | — | — |
| 2MQS | Transient collagen triple helix binding to a key metalloproteinase in invasion and development… | solution nmr | A | — | — |
| 3C7X | Hemopexin-like domain of matrix metalloproteinase 14 | x-ray diffraction | A | — | — |
| 3C7X | Hemopexin-like domain of matrix metalloproteinase 14 | x-ray diffraction | A | — | — |
| 3MA2 | Complex membrane type-1 matrix metalloproteinase (MT1-MMP) with tissue inhibitor of… | x-ray diffraction | D, A | — | — |
| 3MA2 | Complex membrane type-1 matrix metalloproteinase (MT1-mmp) with tissue inhibitor of… | x-ray diffraction | D, A | — | — |
| 3X23 | Radixin complex | x-ray diffraction | B | — | — |
| 3X23 | Radixin complex | x-ray diffraction | B | — | — |
| 4P3C | MT1-MMP:Fab complex (Form I) | x-ray diffraction | M | — | — |
| 4P3C | MT1-MMP:FAB complex (form I) | x-ray diffraction | M | — | — |
| 4P3D | MT1-MMP:Fab complex (Form II) | x-ray diffraction | C, M | — | — |
| 4P3D | MT1-MMP:FAB complex (form II) | x-ray diffraction | C, M | — | — |
| 4QXU | Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational… | x-ray diffraction | K | — | — |
| 4QXU | Novel inhibition mechanism of membrane metalloprotease by an exosite- swiveling conformational… | x-ray diffraction | K | — | — |
| 5H0U | Crystal structure of the catalytic domain of membrane type 1 matrix metalloproteinase | x-ray diffraction | A | — | — |
| 6CLZ | MT1-mmp hpx domain with blade 4 loop bound to nanodiscs | solution nmr | A | PX4, NA, CL | — |
| 6CM1 | MT1-MMP HPX Domain with Blade 2 Loop Bound to Nanodiscs | solution nmr | A | PX4, NA, CL | 1 (best 0.57) |
| 6CM1 | MT1-mmp hpx domain with blade 2 loop bound to nanodiscs | solution nmr | A | PX4, NA, CL | — |
| P50281 | AlphaFold monomer V2.0 prediction for matrix metalloproteinase-14 (P50281) | — | — | — |
Ligands
Elsewhere
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