Research workbench
Crystal structure of oxidation intermediate (1MIN) of NADH-cytochrome B5 reductase from pig liver
Analyse Crystal structure of oxidation intermediate (1MIN) of NADH-cytochrome B5… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3W2H
- Type
- protein
- Length
- 271 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NADH-cytochrome B5 reductase 3
- EC
- 1.6.2.2
- UniProt
- P83686
- Ligands
- FAD, NAD
- Pockets
- 3 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 24% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-cytochrome B5 reductase 3 (EC 1.6.2.2) | protein | 271 | 24% helix, 35% strand | P83686 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · chains A
- NAD · Nicotinamide-adenine-dinucleotide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 435 | 0.61 | 0.76 | 53 | FAD, NAD |
| 2 | 100 | 0.37 | 0.75 | 23 | empty |
| 3 | 54 | 0.30 | 0.76 | 19 | empty |
Compared structures
- 3W2H · Crystal structure of oxidation intermediate (1min) of NADH-cytochrome b5 reductase from… · the same entry in another collection · chain A against A, TM-score 1.00
- P83686 · AlphaFold monomer V2.0 prediction for NADH-cytochrome B5 reductase 3 (P83686) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P83686
- Elsewhere: RCSB PDB 3W2H · PDBe 3W2H · UniProt P83686
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.