Research workbench
The structure of a ternary complex between chea domains P4 and P5 with chew and with a truncated fragment of TM14, a chemoreceptor analog from thermotoga maritima.
Analyse The structure of a ternary complex between chea domains P4 and P5 with chew and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UR1
- Type
- protein
- Length
- 572 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chemotaxis protein chea; Chemotaxis protein chew; Methyl-accepting chemotaxis protein
- EC
- 2.7.13.3
- UniProt
- Q56310, Q56311, Q7DFA3
- Pockets
- 5 · best druggability 0.69
Structure
x-ray diffraction · 3 distinct chains · 24% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chemotaxis protein chea (EC 2.7.13.3) | protein | 263 | 12% helix, 27% strand | Q56310 |
| B | Chemotaxis protein chew | protein | 139 | 10% helix, 38% strand | Q56311 |
| C, D | Methyl-accepting chemotaxis protein | protein | 85 | 82% helix, 0% strand | Q7DFA3 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 587 | 0.69 | 0.78 | 69 | empty |
| 2 | 145 | 0.66 | 0.87 | 33 | empty |
| 3 | 340 | 0.54 | 0.74 | 28 | empty |
| 4 | 74 | 0.40 | 0.79 | 20 | empty |
| 5 | 55 | 0.28 | 0.74 | 11 | empty |
Interfaces
4 interfaces between chains.
- C–D · 1685 Ų buried · 5 hydrogen bonds · protein-protein
- A–B · 886 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 302 Ų buried · 1 hydrogen bond · protein-protein
- B–D · 86 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 3UR1 · The structure of a ternary complex between CheA domains P4 and P5 with CheW and with a… · the same entry in another collection · chain A against A, TM-score 1.00
- Q56311 · AlphaFold monomer V2.0 prediction for chemotaxis protein chew (Q56311) · a predicted model of the same protein · chain B against A, TM-score 0.95
- Q56310 · AlphaFold monomer V2.0 prediction for chemotaxis protein chea (Q56310) · a predicted model of the same protein · chain A against A, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q56310
- Every structure of UniProt Q56311
- Every structure of UniProt Q7DFA3
- Elsewhere: RCSB PDB 3UR1 · PDBe 3UR1 · UniProt Q56310 · UniProt Q56311 · UniProt Q7DFA3
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