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Structure of the TV3 mutant M41E

Analyse Structure of the TV3 mutant M41E in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3UL9
Type: protein
Length: 276 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Toll-like receptor 4, variable lymphocyte receptor B
UniProt: O00206, Q4G1L2
Ligands: NAG, BMA, FUL, SO4

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Toll-like receptor 4, variable lymphocyte receptor B	protein	276	6% helix, 18% strand	O00206, Q4G1L2

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A
BMA · beta-D-mannopyranose · sugar
FUL · beta-L-fucopyranose · sugar
SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 3 disulfide, 2 glycan (disulfide, N-glycosylation).

Compared structures

3UL9 · structure of the TV3 mutant M41E · the same entry in another collection · chain A against A, TM-score 1.00
O00206 · AlphaFold monomer V2.0 prediction for toll-like receptor 4 (O00206) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00206
Every structure of UniProt Q4G1L2
Elsewhere: RCSB PDB 3UL9 · PDBe 3UL9 · UniProt O00206 · UniProt Q4G1L2

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