Research workbench
Mouse importin alpha: nucleoplasmin cnls peptide complex
Analyse Mouse importin alpha: nucleoplasmin cnls peptide complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UL1
- Type
- protein
- Length
- 447 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Importin subunit alpha-2; Nucleoplasmin
- UniProt
- P52293, P05221
- Pockets
- 1 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Importin subunit alpha-2 | protein | 426 | 74% helix, 0% strand | P52293 |
| A | Nucleoplasmin | protein | 21 | 0% helix, 0% strand | P05221 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.38 | 0.78 | 15 | empty |
Interfaces
1 interface between chains.
- B–A · 1381 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 3UL1 · Mouse importin alpha: nucleoplasmin cNLS peptide complex · the same entry in another collection · chain B against B, TM-score 1.00
- P52293 · AlphaFold monomer V2.0 prediction for importin subunit alpha-1 (P52293) · a predicted model of the same protein · chain B against A, TM-score 0.99
- P05221 · AlphaFold monomer V2.0 prediction for nucleoplasmin (P05221) · a predicted model of the same protein · chain A against A, TM-score 0.16
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52293
- Every structure of UniProt P05221
- Elsewhere: RCSB PDB 3UL1 · PDBe 3UL1 · UniProt P52293 · UniProt P05221
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