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Crystal structure of the MDA5 helicase insert domain

Analyse Crystal structure of the MDA5 helicase insert domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3TS9
Type
protein
Length
128 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Interferon-induced helicase C domain-containing protein 1
EC
3.6.4.13
UniProt
Q8R5F7
Ligands
SO4

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AInterferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13)protein12878% helix, 0% strandQ8R5F7

Ligands and binding sites

  • SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 3TS9 · Crystal Structure of the MDA5 Helicase Insert Domain · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8R5F7 · AlphaFold monomer V2.0 prediction for interferon-induced helicase C domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.97

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