Research workbench

Calmodulin mutant with a two residue deletion in the central helix

Analyse Calmodulin mutant with a two residue deletion in the central helix in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1AHR
Type: protein
Length: 146 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calmodulin
UniProt: P62149
Ligands: CA
Pockets: 2 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 57% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calmodulin	protein	146	57% helix, 7% strand	P62149

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.50	0.82	13	empty
2	116	0.48	0.78	16	empty

Compared structures

1AHR · Calmodulin mutant with a two residue deletion in the central helix · the same entry in another collection · chain A against A, TM-score 1.00
P62149 · AlphaFold monomer V2.0 prediction for calmodulin (P62149) · a predicted model of the same protein · chain A against A, TM-score 0.59

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62149
Elsewhere: RCSB PDB 1AHR · PDBe 1AHR · UniProt P62149

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