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Crystal structure of human lfabp complex with two molecules of palmitic acid (holo-lfabp)

Analyse Crystal structure of human lfabp complex with two molecules of palmitic acid… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3STK
Type: protein
Length: 129 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fatty acid-binding protein, liver
UniProt: P07148
Ligands: PLM
Pockets: 1 · best druggability 0.86

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 58% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fatty acid-binding protein, liver	protein	129	12% helix, 58% strand	P07148

Ligands and binding sites

PLM · Palmitic acid · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	438	0.86	0.93	45	PLM

Compared structures

3STK · Crystal Structure of human LFABP complex with two molecules of palmitic acid (holo-LFABP) · the same entry in another collection · chain A against A, TM-score 1.00
P07148 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein, liver (P07148) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07148
Elsewhere: RCSB PDB 3STK · PDBe 3STK · UniProt P07148

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