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Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia ptb domain

Analyse Crystal structure of the LDL receptor tail in complex with autosomal recessive… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3SO6
Type
protein
Length
150 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
LDL receptor adaptor protein; Low-density lipoprotein receptor
UniProt
D3ZAR1, P01130

Structure

x-ray diffraction · 2 distinct chains · 29% helix, 38% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALDL receptor adaptor proteinprotein13731% helix, 39% strandD3ZAR1
QLow-density lipoprotein receptorprotein130% helix, 31% strandP01130

Interfaces

1 interface between chains.

  • A–Q · 850 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

  • 3SO6 · Crystal structure of the LDL receptor tail in complex with autosomal recessive… · the same entry in another collection · chain A against A, TM-score 1.00
  • D3ZAR1 · AlphaFold monomer V2.0 prediction for low density lipoprotein receptor adapter protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.94
  • P01130 · AlphaFold monomer V2.0 prediction for low-density lipoprotein receptor (P01130) · a predicted model of the same protein · chain Q against A, TM-score 0.35

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