UniProt P01130
Low-density lipoprotein receptor (P01130)
Low-density lipoprotein receptor (UniProt P01130): 62 experimental structures on GenesisL1, 2 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P01130
- Protein
- Low-density lipoprotein receptor
- Experimental structures
- 62
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 13 · 3 records with a druggable one
Structures
62 records of P01130 in the MolNFT archive: 62 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AJJ | LDL receptor ligand-binding module 5, calcium-coordinating | x-ray diffraction | A | — | — |
| 1AJJ | LDL receptor ligand-binding module 5, calcium-coordinating | x-ray diffraction | A | — | — |
| 1D2J | LDL receptor ligand-binding module 6 | solution nmr | A | — | — |
| 1D2J | LDL receptor ligand-binding module 6 | solution nmr | A | — | — |
| 1F5Y | NMR structure of a concatemer of the first and second ligand-binding modules of the human LDL… | solution nmr | A | — | — |
| 1F5Y | NMR structure of a concatemer of the first and second ligand-binding modules of the human LDL… | solution nmr | A | — | — |
| 1F8Z | NMR structure of the sixth ligand-binding module of the LDL receptor | solution nmr | A | — | — |
| 1F8Z | NMR structure of the sixth ligand-binding module of the LDL receptor | solution nmr | A | — | — |
| 1HJ7 | NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures | solution nmr | A | — | — |
| 1HJ7 | NMR study of a pair of LDL receptor CA2+ binding epidermal growth factor-like domains, 20 structures | solution nmr | A | — | — |
| 1HZ8 | Solution structure and backbone dynamics of a concatemer of EGF-homology modules of the human low… | solution nmr | A | — | — |
| 1HZ8 | Solution structure and backbone dynamics of a concatemer of EGF- homology modules of the human low… | solution nmr | A | — | — |
| 1I0U | Solution structure and backbone dynamics of a concatemer of EGF-homology modules of the human low… | solution nmr | A | — | — |
| 1I0U | Solution structure and backbone dynamics of a concatemer of EGF- homology modules of the human low… | solution nmr | A | — | — |
| 1IJQ | Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair | x-ray diffraction | A, B | — | — |
| 1IJQ | Crystal structure of the LDL receptor ywtd-EGF domain pair | x-ray diffraction | A, B | — | — |
| 1LDL | Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor | solution nmr | A | — | — |
| 1LDL | Three-dimensional structure of a cysteine-rich repeat from the low- density lipoprotein receptor | solution nmr | A | — | — |
| 1LDR | Second repeat of the LDL receptor ligand-binding domain | solution nmr | A | — | — |
| 1LDR | Second repeat of the LDL receptor ligand-binding domain | solution nmr | A | — | — |
| 1N7D | Extracellular domain of the LDL receptor | x-ray diffraction | A | — | — |
| 1N7D | Extracellular domain of the LDL receptor | x-ray diffraction | A | — | — |
| 1XFE | Solution structure of the LA7-EGFA pair from the LDL receptor | solution nmr | A | — | — |
| 1XFE | Solution structure of the LA7-egfa pair from the LDL receptor | solution nmr | A | — | — |
| 2FCW | Structure of a Complex Between the Pair of the LDL Receptor Ligand-Binding Modules 3-4 and the… | x-ray diffraction | B | — | — |
| 2FCW | Structure of a complex between the pair of the LDL receptor ligand- binding modules 3-4 and the… | x-ray diffraction | B | — | — |
| 2KRI | Structure of a complex between domain V of beta2-glycoprotein I and the fourth ligand-binding… | solution nmr | B | — | — |
| 2KRI | Structure of a complex between domain V of BETA2-glycoprotein I and the fourth ligand-binding… | solution nmr | B | — | — |
| 2LGP | Solution structure of LA45 from LDLR | solution nmr | A | — | — |
| 2LGP | Solution structure of LA45 from ldlr | solution nmr | A | — | — |
| 2M7P | RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor… | solution nmr | A | — | — |
| 2M7P | RXFP1 utilises hydrophobic moieties on a signalling surface of the ldla module to mediate receptor… | solution nmr | A | — | — |
| 2MG9 | Truncated EGF-A | solution nmr | A | — | — |
| 2MG9 | Truncated EGF-a | solution nmr | A | — | — |
| 2W2M | Wt PCSK9-deltac bound to wt EGF-a of ldlr | x-ray diffraction | E | — | — |
| 2W2M | Wt PCSK9-deltac bound to wt EGF-a of ldlr | x-ray diffraction | E | — | — |
| 2W2N | WT PCSK9-deltaC bound to EGF-A H306Y mutant of LDLR | x-ray diffraction | E | — | — |
| 2W2N | Wt PCSK9-deltac bound to EGF-a H306Y mutant of ldlr | x-ray diffraction | E | — | — |
| 2W2O | PCSK9-deltaC D374Y mutant bound to WT EGF-A of LDLR | x-ray diffraction | E | — | — |
| 2W2O | PCSK9-deltac D374Y mutant bound to wt EGF-a of ldlr | x-ray diffraction | E | — | — |
| 2W2P | PCSK9-deltaC D374A mutant bound to WT EGF-A of LDLR | x-ray diffraction | E | — | — |
| 2W2P | PCSK9-deltac D374A mutant bound to wt EGF-a of ldlr | x-ray diffraction | E | — | — |
| 2W2Q | PCSK9-deltaC D374H mutant bound to WT EGF-A of LDLR | x-ray diffraction | E | — | — |
| 2W2Q | PCSK9-deltac D374H mutant bound to wt EGF-a of ldlr | x-ray diffraction | E | — | — |
| 3BPS | PCSK9:EGF-A complex | x-ray diffraction | E | — | — |
| 3BPS | PCSK9:EGF-a complex | x-ray diffraction | E | — | — |
| 3GCW | PCSK9:EGFA(H306Y) | x-ray diffraction | E | — | — |
| 3GCW | PCSK9:EGFA(H306Y) | x-ray diffraction | E | — | — |
| 3GCX | PCSK9:EGFA (pH 7.4) | x-ray diffraction | E | — | — |
| 3GCX | PCSK9:EGFA (pH 7.4) | x-ray diffraction | E | — | — |
| 3M0C | The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor | x-ray diffraction | C | — | — |
| 3M0C | The X-ray crystal structure of PCSK9 in complex with the LDL receptor | x-ray diffraction | C | — | — |
| 3SO6 | Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia… | x-ray diffraction | Q | — | — |
| 3SO6 | Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia… | x-ray diffraction | Q | — | — |
| 4NE9 | PCSK9 in complex with LDLR peptide | x-ray diffraction | D | — | — |
| 4NE9 | PCSK9 in complex with ldlr peptide | x-ray diffraction | D | — | — |
| 5OY9 | VSV G CR3 | x-ray diffraction | D | CA | — |
| 5OYL | VSV G CR2 | x-ray diffraction | D | CA | — |
| 9BDE | Middle Region of Apolipoprotein B 100 bound to Low Density Lipoprotein Receptor | electron microscopy | R | NAG, CA | 6 (best 0.53) |
| 9BDT | Apolipoprotein B 100 bound to LDL receptor and legobody | electron microscopy | I, R | NAG, CA | 4 (best 0.60) |
2 records more on the page itself.
Ligands
Elsewhere
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