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Structure of D13, the scaffolding protein of vaccinia virus
Analyse Structure of D13, the scaffolding protein of vaccinia virus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3SAQ
- Type
- protein
- Length
- 957 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Rifampicin resistance protein
- UniProt
- P68440
- Pockets
- 14 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 17% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rifampicin resistance protein | protein | 465 | 17% helix, 40% strand | P68440 |
| B | Rifampicin resistance protein | protein | 492 | 16% helix, 43% strand | P68440 |
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 725 | 0.77 | 0.82 | 64 | empty |
| 2 | 663 | 0.76 | 0.82 | 62 | empty |
| 3 | 801 | 0.76 | 0.80 | 73 | empty |
| 4 | 202 | 0.71 | 0.88 | 34 | empty |
| 5 | 172 | 0.60 | 0.82 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 665 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 3SAQ · Structure of D13, the scaffolding protein of vaccinia virus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P68440
- Elsewhere: RCSB PDB 3SAQ · PDBe 3SAQ · UniProt P68440
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