Research workbench
Complex of influenza virus protein with host anti-viral factor
Analyse Complex of influenza virus protein with host anti-viral factor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3RT3
- Type
- protein
- Length
- 247 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin-like protein ISG15; Non-structural protein 1
- UniProt
- P05161, P03502
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Ubiquitin-like protein ISG15 | protein | 153 | 25% helix, 33% strand | P05161 |
| C | Non-structural protein 1 | protein | 94 | 76% helix, 0% strand | P03502 |
Ligands and binding sites
- SIN · Succinic acid · additive · 2 copies · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.28 | 0.74 | 12 | empty |
Interfaces
1 interface between chains.
- B–C · 419 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 3RT3 · Complex of influenza virus protein with host anti-viral factor · the same entry in another collection · chain B against B, TM-score 1.00
- P05161 · AlphaFold monomer V2.0 prediction for ubiquitin-like protein ISG15 (P05161) · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05161
- Every structure of UniProt P03502
- Elsewhere: RCSB PDB 3RT3 · PDBe 3RT3 · UniProt P05161 · UniProt P03502
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