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Solution structure and ligand-binding site of the C-terminal SH3 domain of GRB2

Analyse Solution structure and ligand-binding site of the C-terminal SH3 domain of GRB2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1GFD
Type
protein
Length
59 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Growth factor receptor-bound protein 2
UniProt
P62993

Structure

solution nmr · 1 distinct chain · 5% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGrowth factor receptor-bound protein 2protein595% helix, 29% strandP62993

Compared structures

  • 1GFD · Solution structure and ligand-binding site of the C-terminal SH3 domain of GRB2 · the same entry in another collection · chain A against A, TM-score 1.00
  • P62993 · AlphaFold monomer V2.0 prediction for growth factor receptor-bound protein 2 (P62993) · a predicted model of the same protein · chain A against A, TM-score 0.89

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