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Crystal structure of wt protective antigen (pH 5.5)

Analyse Crystal structure of wt protective antigen (pH 5.5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3Q8A
Type: protein
Length: 673 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protective antigen
UniProt: P13423
Ligands: CA
Pockets: 8 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protective antigen	protein	673	14% helix, 32% strand	P13423

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	590	0.68	0.78	67	empty
2	156	0.55	0.81	25	empty
3	98	0.55	0.85	23	empty
4	172	0.53	0.79	18	empty
5	150	0.45	0.76	24	empty

Compared structures

3Q8A · Crystal structure of WT Protective Antigen (pH 5.5) · the same entry in another collection · chain A against A, TM-score 1.00
P13423 · AlphaFold monomer V2.0 prediction for protective antigen (P13423) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13423
Elsewhere: RCSB PDB 3Q8A · PDBe 3Q8A · UniProt P13423

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