Research workbench
Structure of the central region of the plakin domain of plectin
Analyse Structure of the central region of the plakin domain of plectin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3PE0
- Type
- protein
- Length
- 542 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plectin
- UniProt
- Q15149
- Ligands
- CA
- Pockets
- 2 · best druggability 0.45
Structure
x-ray diffraction · 2 distinct chains · 67% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plectin | protein | 271 | 67% helix, 10% strand | Q15149 |
| B | Plectin | protein | 271 | 67% helix, 11% strand | Q15149 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 108 | 0.45 | 0.79 | 24 | empty |
| 2 | 124 | 0.44 | 0.77 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 40 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3PE0 · Structure of the central region of the plakin domain of plectin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15149
- Elsewhere: RCSB PDB 3PE0 · PDBe 3PE0 · UniProt Q15149
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.